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Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

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Published on: October 18, 2012

Wells Syndrome-Like Histologic Pattern Caused by a Permanent Tattoo.

Maha Kazmi¹, Ashley Elsensohn², Jacqueline M Junkins-Hopkins³

¹University of California Davis School of Medicine, Sacramento, CA.

The American Journal of Dermatopathology

|February 4, 2022

Summary

This summary is machine-generated.

Tattoo reactions are increasing globally. This study details the first permanent tattoo case exhibiting flame figures, a pattern histologically similar to Wells syndrome, previously only seen with temporary henna tattoos.

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Area of Science:

Dermatology
Pathology

Background:

Tattoo popularity is rising globally, leading to more reported tattoo reactions.
Various inflammatory patterns, including granulomatous and spongiotic, are associated with tattoos.
A rare Wells syndrome-like reaction was previously reported with temporary henna tattoos.

Observation:

This report presents the first case of a permanent tattoo reaction.
The reaction displayed flame figures on histological examination.
These findings histologically mimicked Wells syndrome.

Findings:

Permanent tattoos can induce inflammatory reactions with unique histological patterns.
Flame figures, characteristic of Wells syndrome, were observed in a permanent tattoo reaction.
This represents an uncommon histologic presentation for permanent tattoos.

Implications:

Pathologists should consider Wells syndrome-like reactions in permanent tattoo complications.
Awareness of this pattern aids in accurate diagnosis of tattoo-associated dermatoses.
This finding expands the spectrum of known tattoo reactions and their histological manifestations.