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Updated: Oct 4, 2025
04:05
Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
107
Risk factors associated to intestinal anastomotic leakage in elective surgery
Martín A Bolívar-Rodríguez1, Francisco Magaña-Olivas1, Marcel A Cázarez-Aguilar1
1Servicio de Cirugía General.
Cirugia Y Cirujanos
|February 4, 2022
Summary
Intestinal anastomotic leakage is a feared surgical complication. This study identified cocaine use, cancer, neoadjuvant therapy, and end-to-end anastomosis as significant risk factors for leakage in elective surgery.
Area of Science:
- Gastrointestinal Surgery
- Surgical Complications
- Oncology
Background:
- Intestinal anastomotic leakage is a major complication in digestive surgery.
- It significantly increases patient morbidity, mortality, and hospital stay.
Purpose of the Study:
- To identify risk factors for intestinal anastomotic leakage in elective surgical procedures.
Main Methods:
- Retrospective observational study.
- Inclusion of patients undergoing intestinal anastomosis in elective surgery between January 2007 and January 2017.
- Analysis of 64 patients, with 7 experiencing anastomotic leakage.
Main Results:
- Cocaine use (p=0.030), neoplasia (p=0.008), neoadjuvant cancer treatment (p=0.003), and end-to-end anastomosis (p=0.037) were significant risk factors.
- Patients with leakage experienced longer hospital stays.
- Mortality rate for patients with leakage was 14.3%.
Conclusions:
- Identified risk factors align with existing global literature.
- Cocaine use emerged as a statistically significant, noteworthy risk factor in this patient cohort.
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