Related Experiment Video
Updated: Oct 4, 2025

Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
Published on: February 10, 2023
Anesthesia Considerations in Infective Endocarditis
Henning Hermanns1, Susanne Eberl1, Lotte E Terwindt1
1From the Department of Anesthesiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Insights
Infective endocarditis management is complex, often requiring urgent cardiac surgery. Anesthesiologists play a crucial role in perioperative care for these unique cardiac surgery patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Anesthesiology
Background:
- Infective endocarditis (IE) management is complex, necessitating multidisciplinary collaboration.
- Approximately 50% of IE patients require cardiac surgery, often in urgent or emergency settings.
- IE presents unique challenges in cardiac surgery due to its pathophysiology and clinical manifestations.
Purpose of the Study:
- To review current knowledge on infective endocarditis relevant to anesthesiologists.
- To highlight specific perioperative considerations for IE patients undergoing cardiac surgery.
- To advocate for the anesthesiologist's integral role in the endocarditis team.
Main Methods:
- This article is a narrative review.
- It synthesizes existing literature on infective endocarditis and perioperative management.
- Focuses on aspects critical for clinical anesthesiologists.
Main Results:
- Infective endocarditis requires specialized perioperative management.
- Key areas include echocardiography, coagulation, bleeding management, and organ dysfunction treatment.
- Anesthesiologists need a thorough understanding of IE's unique perioperative characteristics.
Conclusions:
- Anesthesiologists are vital members of the endocarditis management team.
- Integrating anesthesiologists structurally enhances perioperative care for IE patients.
- Multidisciplinary cooperation is essential for optimal outcomes in infective endocarditis management.
Abstract:
The management of infective endocarditis is complex and inherently requires multidisciplinary cooperation. About half of all patients diagnosed with infective endocarditis will meet the criteria to undergo cardiac surgery, which regularly takes place in urgent or emergency settings. The pathophysiology and clinical presentation of infective endocarditis make it a unique disorder within cardiac surgery that warrants a thorough understanding of specific characteristics in the perioperative period. This includes, among others, echocardiography, coagulation, bleeding management, or treatment of organ dysfunction. In this narrative review article, the authors summarize the current knowledge on infective endocarditis relevant for the clinical anesthesiologist in perioperative management of respective patients. Furthermore, the authors advocate for the anesthesiologist to become a structural member of the endocarditis team.
Related Concept Videos
Endocarditis IV: Nursing Management
Endocarditis III: Medical Management
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Myocarditis III: Medical Management
Aneurysm IV: Nursing Management

