Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

2.0K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
2.0K
Development of Blood Vessels01:07

Development of Blood Vessels

871
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
871
Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

3.0K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
3.0K
Fetal Circulation01:14

Fetal Circulation

1.6K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
1.6K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

7.7K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.7K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

8.2K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
8.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oncogenic Gαq Signaling Remodels the Tumor Surfaceome and Rewires Intracellular Networks in Uveal Melanoma Models.

Cancers·2026
Same author

Three-Dimensional Analysis of Eyelid Morphological Outcomes After Hughes Flap Reconstruction for Full-Thickness Lower Eyelid Defects.

Aesthetic plastic surgery·2026
Same author

Three-dimensional stereophotogrammetry for periocular tumors: Reproducibility and clinical feasibility.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2026
Same author

Nomogram for predicting implant exposure risk following enucleation or evisceration with vicryl-meshed hydroxyapatite implants.

The British journal of ophthalmology·2026
Same author

Intravenous chemotherapy versus intra-arterial chemotherapy for retinoblastoma.

The Cochrane database of systematic reviews·2026
Same author

Four Months of Exercise Intervention Improved Visuomotor, Functional and Cardiorespiratory Capacity in a Patient with Metastatic Uveal Melanoma.

Reports (MDPI)·2025

Related Experiment Video

Updated: Oct 4, 2025

Three-Dimensional Reconstruction of Orbital Fractures
08:18

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

351

Fetal Development of the Orbit.

Piotr Jakub Gaca1, Michael Lewandowicz2, Malgorzata Lipczynska-Lewandowska3

  • 1Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Klinische Monatsblatter Fur Augenheilkunde
|February 4, 2022
PubMed
Summary

This study details the fetal period of human orbital development, outlining key milestones in orbital morphogenesis. Understanding these developmental processes is vital for addressing congenital orbital deformities.

More Related Videos

Grossing of Non-neoplastic Globes, Including Fetal Eyes
05:15

Grossing of Non-neoplastic Globes, Including Fetal Eyes

Published on: May 30, 2025

224
Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
04:48

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

3.0K

Related Experiment Videos

Last Updated: Oct 4, 2025

Three-Dimensional Reconstruction of Orbital Fractures
08:18

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

351
Grossing of Non-neoplastic Globes, Including Fetal Eyes
05:15

Grossing of Non-neoplastic Globes, Including Fetal Eyes

Published on: May 30, 2025

224
Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
04:48

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

3.0K

Area of Science:

  • Developmental biology
  • Human embryology
  • Ophthalmology

Background:

  • Human prenatal development includes embryonic and fetal periods, with the embryonic phase characterized by intense organogenesis.
  • The fetal period involves less dramatic developmental changes but is crucial for refining structures like the orbit.
  • Understanding orbital embryology is key to explaining normal variations and congenital deformities.

Purpose of the Study:

  • To summarize the major milestones in orbital morphogenesis during the fetal period.
  • To enhance the understanding of the developmental anatomy of the orbit.
  • To provide a foundation for future research into orbital diseases.

Main Methods:

  • Review and synthesis of existing literature on orbital development.
  • Temporal mapping of key morphogenetic events.
  • Focus on the anatomical, biochemical, and molecular aspects of orbital development.

Main Results:

  • Detailed summary of orbital morphogenesis milestones during fetal development.
  • Description of the process as a complex series of anatomical, biochemical, and molecular events.
  • Identification of the intricate coordination required for normal orbital development.

Conclusions:

  • Orbital morphogenesis is a precise and intricate process involving coordinated anatomical and molecular events.
  • Further research into signaling pathways and regulatory genes is essential for future treatments.
  • Understanding fetal orbital development is critical for managing congenital orbital conditions.