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Updated: Oct 4, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

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Synthesis and SAR of novel GPR39 agonists and positive allosteric modulators

Russell Burley1, Richard C Hewer1, Martin Teall1

  • 1Cerevance Ltd, 418 Cambridge Science Park, Milton Road, Cambridge CB4 0PZ, UK.

Bioorganic & Medicinal Chemistry Letters
|February 5, 2022
PubMed

Keywords:
AgonistG protein-coupled receptorGPR39Parkinson’s disease

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