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Related Concept Videos

Adhesion01:14

Adhesion

42.0K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
42.0K

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Updated: Oct 4, 2025

A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux': Preparation and Demonstration
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Chitosan based bioadhesives for biomedical applications: A review.

Hamid Hamedi1, Sara Moradi2, Samuel M Hudson1

  • 1Textile Engineering Chemistry and Science, Fiber & Polymer Science Program, Wilson College of Textiles, North Carolina State University, Raleigh, NC, USA.

Carbohydrate Polymers
|February 6, 2022
PubMed
Summary

Chitosan bioadhesives show great potential for biomedical uses. These materials demonstrate effective wound healing, hemostatic, and bioadhesion capabilities, making them valuable for various medical applications.

Keywords:
BioadhesivesChitosanDrug deliverySuture less surgeryWound dressing

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Biomedical Engineering

Background:

  • Chitosan is a highly promising biopolymer due to its biodegradability, biocompatibility, and non-toxicity.
  • Its unique properties have led to significant interest in chitosan and its derivatives for diverse biomedical applications.
  • Chitosan-based materials are being explored to overcome limitations in current medical treatments.

Purpose of the Study:

  • To review different types of chitosan-based bioadhesives, including passive and active systems.
  • To discuss chitosan bioadhesives responsive to external stimuli like temperature, pH, and light.
  • To present various bioadhesive mechanisms and potential biomedical applications of chitosan.

Main Methods:

  • Literature review of chitosan-based bioadhesives and their properties.
  • Analysis of different chitosan derivative structures and their stimuli-responsive mechanisms.
  • Compilation of examples and discussion of applications in drug delivery, surgery, wound care, and hemostasis.

Main Results:

  • Chitosan bioadhesives exhibit excellent wound healing properties.
  • Effective hemostatic capabilities were confirmed for chitosan-based materials.
  • Strong bioadhesion characteristics were demonstrated, highlighting their potential.

Conclusions:

  • Chitosan bioadhesives possess significant potential for advanced biomedical applications.
  • Their wound healing, hemostatic, and bioadhesion properties make them suitable for sutureless surgery and wound dressings.
  • Further development of chitosan bioadhesives can lead to innovative solutions in drug delivery and hemostasis.