Postintensive care syndrome in COVID-19. Unicentric pilot study
Eva Mateo Rodríguez1, Francesc Puchades Gimeno2, Aida Ezzeddine Angulo3
1UCI de Anestesia, Servicio de Anestesiología, Consorci Hospital General Universitari de València, Valencia, España.
Nine out of ten COVID-19 survivors experienced Postintensive Care Syndrome (PICS) symptoms, including physical, cognitive, or psychiatric issues, weeks after hospital discharge. This highlights the long-term impact of critical illness on patient recovery.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Neurology
Background:
- Postintensive Care Syndrome (PICS) encompasses physical, cognitive, and psychiatric impairments following critical illness.
- COVID-19 survivors admitted to intensive care units (ICUs) are at risk for developing PICS.
- Understanding PICS prevalence in COVID-19 patients is crucial for long-term patient management.
Purpose of the Study:
- To determine the prevalence of Postintensive Care Syndrome (PICS) in patients who were admitted to the ICU for COVID-19.
- To assess various PICS domains including quality of life, physical function, cognition, mental health, and pain.
Main Methods:
- A cohort of 29 COVID-19 patients admitted to the ICU were assessed 4-6 weeks post-discharge.
- Standardized assessments included EuroQol-5D-3L for quality of life, 6 MWT and "test up and go" for physical status, MUST for nutrition, MoCA for cognition, HADS and Davidson Trauma Scale for mental health, and pain scales.
- Data on ICU and mechanical ventilation duration, SOFA scores, and interventions like tracheostomy and pronation were collected.
Main Results:
- 90% of COVID-19 survivors studied exhibited at least one PICS alteration.
- 6 out of 19 patients (31.6%) presented with two or more affected areas.
- High rates of tracheostomy (52%) and pronation (93%) were noted in the ICU population.
Conclusions:
- The vast majority of COVID-19 survivors admitted to the ICU develop Postintensive Care Syndrome (PICS).
- PICS affects multiple domains, including physical, cognitive, and psychiatric health, persisting weeks after hospital discharge.
- Early and comprehensive assessment for PICS is essential for survivors of severe COVID-19.
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