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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

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Cardiovascular Diseases in the Patients With Psoriatic Arthritis

Anum Akhlaq1, Huma Fatima Ali2, Abu Baker Sheikh3

  • 1Department of Internal Medicine, University of Mississippi Medical Center, MS, USA.

Current Problems in Cardiology
|February 6, 2022
PubMed

Insights

Cardiovascular disease hospitalizations, including heart failure, heart attack, and stroke, showed an increasing trend in psoriatic arthritis patients. While costs decreased for heart failure, overall mortality and length of stay remained unchanged.

Area of Science:

  • Rheumatology
  • Cardiology
  • Public Health

Background:

  • Psoriatic arthritis (PsA) is associated with an increased risk of cardiovascular diseases (CVD).
  • Limited data exists on the national burden and trends of CVD hospitalizations in PsA patients.

Purpose of the Study:

  • To analyze hospitalization trends for heart failure (HF), acute myocardial infarction (AMI), and stroke in adults with PsA.
  • To evaluate in-hospital mortality, length of stay (LOS), and inflation-adjusted costs associated with these hospitalizations.

Main Methods:

  • Analysis of the National Inpatient Sample (NIS) database from January 2005 to December 2018.
  • Examination of age-adjusted hospitalization percentages for HF, AMI, and stroke among PsA patients.
  • Assessment of trends in in-hospital mortality, LOS, and inflation-adjusted costs.

Main Results:

  • Age-adjusted HF hospitalizations decreased then increased, with a significant trend over time (P-trend 0.044).
  • AMI hospitalizations showed a non-significant decreasing trend followed by a non-significant increase (P-trend 0.056).
  • Age-adjusted stroke hospitalizations demonstrated a significant increasing trend (P-trend 0.036).
  • No significant changes in inpatient mortality or LOS were observed; inflation-adjusted costs decreased for HF hospitalizations.

Conclusions:

  • There is an increasing trend of cardiovascular hospitalizations in patients with psoriatic arthritis.
  • Findings highlight the need for increased awareness and further research into CVD management in PsA.
  • These results can inform clinical practice for managing cardiovascular risks in PsA patients.

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