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Eikenella corrodens.

M D Decker

    Infection Control : IC
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Eikenella corrodens, a common oral bacterium, can cause serious infections. Recognizing its presence and understanding antibiotic sensitivities are crucial for effective treatment, especially in bite wounds.

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    Area of Science:

    • Microbiology
    • Infectious Diseases

    Background:

    • Eikenella corrodens is a microaerophilic, gram-negative bacterium normally found on human mucosal surfaces, primarily the oral cavity.
    • While often part of mixed infections, it can independently cause severe infections in both healthy and immunocompromised individuals.

    Purpose of the Study:

    • To highlight the clinical significance of Eikenella corrodens infections.
    • To emphasize the importance of laboratory recognition and appropriate antibiotic selection for Eikenella infections.

    Main Methods:

    • Literature review and analysis of clinical case data.
    • Discussion of Eikenella corrodens' microbiological characteristics and growth requirements.
    • Review of antibiotic susceptibility patterns.

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    Main Results:

    • Eikenella corrodens infections may be under-recognized due to its slow growth and specific culture needs.
    • Inappropriate antibiotic choices (e.g., clindamycin, metronidazole) can lead to pure Eikenella infections.
    • Penicillin, tetracycline, and chloramphenicol show general effectiveness; cephalexin and dicloxacillin are ineffective.

    Conclusions:

    • Alerting clinical laboratories to the possibility of Eikenella corrodens is important, particularly in head and neck or human bite wound infections.
    • Third-generation cephalosporins and cefoxitin are highly effective against Eikenella.
    • Appropriate antibiotic therapy is essential to prevent the emergence of monomicrobial Eikenella infections.