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Chronodisruption and cardiovascular disease.

Antonio Garcia-Rios1, Jose M Ordovas2

  • 1Lipids and Atherosclerosis Unit, Maimonides Institute for Biomedical Research in Cordoba (IMIBIC), Reina Sofia University Hospital, University of Córdoba, 14004 Córdoba, Spain; CIBEROBN (CIBER in Physiopathology of Obesity and Nutrition), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Clinica E Investigacion En Arteriosclerosis : Publicacion Oficial De La Sociedad Espanola De Arteriosclerosis
|February 7, 2022
PubMed
Summary

Cardiovascular disease (CVD) risk increases with circadian disruption, a disturbance in biological rhythms. Addressing chronobiology is crucial for managing CVD and its associated health burdens.

Keywords:
Cardiovascular diseaseChronobiologyChronodisruptionCronobiologíaCronodisrupciónDietDietaEnfermedad cardiovascularNutriciónNutrition

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Area of Science:

  • Chronobiology and cardiovascular health.
  • Focus on biological rhythms and disease.
  • Temporal regulation in physiology.

Background:

  • Cardiovascular disease (CVD) poses a significant global health challenge.
  • Rising prevalence of cardiometabolic risk factors exacerbates CVD.
  • Traditional risk factor control is insufficient to curb the CVD pandemic.

Purpose of the Study:

  • To review evidence linking chronobiology to cardiovascular disease.
  • To highlight the emerging role of circadian rhythms in CVD research.
  • To advocate for the integration of chronobiology into clinical practice.

Main Methods:

  • Review of scientific literature on chronobiology and CVD.
  • Analysis of studies on circadian disruption and cardiovascular risk.
  • Synthesis of evidence on the impact of disturbed biological rhythms.

Main Results:

  • Circadian disruption significantly elevates the risk of developing CVD.
  • Chronobiology offers a novel perspective on CVD pathogenesis.
  • Disturbances in physiological rhythms are linked to increased cardiovascular risk.

Conclusions:

  • Chronobiology is a critical emerging field for understanding and managing CVD.
  • Addressing circadian disruption is essential for combating the CVD pandemic.
  • Translating chronobiological evidence into clinical practice is imperative.