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Updated: Oct 4, 2025
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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
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Acquisition of peak bone mass.
Thierry Chevalley1, René Rizzoli1
1Service of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
Best Practice & Research. Clinical Endocrinology & Metabolism
|February 7, 2022
Summary
Peak bone mass (PBM) is crucial for preventing fractures. Optimizing nutrition and physical activity during growth significantly enhances PBM acquisition and bone strength.
Area of Science:
- Bone Biology and Health
- Pediatric Endocrinology
- Nutritional Science
Background:
- Peak bone mass (PBM) is a critical determinant of skeletal health and future fracture risk.
- Bone mass increases significantly during childhood and adolescence, primarily through bone size expansion rather than density changes.
Purpose of the Study:
- To highlight the key determinants of PBM achievement.
- To emphasize the role of environmental factors in bone mass accrual during growth.
- To advocate for strategies to optimize PBM for lifelong bone health.
Main Methods:
- Review of established literature on bone mass development.
- Analysis of factors influencing bone accrual during growth.
- Synthesis of evidence on nutritional and physical activity interventions.
Main Results:
- PBM is influenced by race, gender, and genetics.
- Environmental factors like physical activity, calcium and protein intake, and menarche timing play significant roles.
- Bone size increase is the primary driver of bone mass accrual during adolescence.
Conclusions:
- Optimizing calcium and protein intake is vital for bone health.
- Weight-bearing physical activity during growth is essential for maximizing PBM.
- Early life interventions are key to preventing osteoporosis and fractures later in life.
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