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Updated: Oct 4, 2025

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
Published on: October 16, 2010
Breastfeeding and Reduced Risk of Breast Cancer: A Systematic Review and Meta-Analysis
Rongbin Qiu1, Yangjian Zhong1, Mengmeng Hu1
1The First Affiliated Hospital of Nanchang University, China.
Background:
Evidences which prove relation between breastfeeding women and risk of breast cancer have been limited.
Objective:
A meta-analysis was carried out on the basis of published literature from clinical trials and studies among different parts of the world.
Methods:
Studies were analyzed and extracted using PRISMA flowchart. RevMan 5.4.1 was used for analyzing the extracted data. Included studies were fully cited texts with complete information about studies, trails conducted for risk of breast cancer, and breastfeeding correlations.
Results:
Menarche age, family history, lactation duration, and menopausal status have a strong effect on the risks of breast cancer. Family history studies concluded that for 95% CI, the risk ratio was 2.66 (2.00, 3.52).
Conclusion:
Findings have suggested that family history and lactation duration affect the risks of breast cancer.
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