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Vitamin E
Area of Science:
- Biochemistry and Pediatrics
Context:
- The precise biochemical mechanisms of vitamin E remain incompletely understood.
- Clinical applications of vitamin E are being explored, particularly in pediatric care.
Purpose:
- To review the established and potential clinical uses of vitamin E in pediatrics.
- To highlight conditions where vitamin E supplementation is considered, including hemolytic anemia in preterm infants, hereditary bullous epidermolysis, retrolental fibroplasia, and bronchopulmonary dysplasia.
Summary:
- This review examines the empirical clinical applications of vitamin E in pediatrics.
- Conditions discussed include hemolytic anemia in preterm infants, hereditary bullous epidermolysis, retrolental fibroplasia, and bronchopulmonary dysplasia.
- The potential toxicity of excess vitamin E necessitates careful consideration.
Impact:
- Provides a concise overview of vitamin E's pediatric applications.
- Highlights the need for further research into vitamin E's mechanisms.
- Emphasizes the importance of monitoring vitamin E dosage to avoid toxicity.
Abstract:
The biochemical mechanism of vitamin E cannot be explained up to the moment. Empirically, there are several possibilities for the clinical use of vitamin E, especially in pediatrics. This review is focusing on the hemolytic anemia of the preterm infant, hereditary bullous epidermolysis, retrolental fibroplasia and bronchopulmonary dysplasia. Excess vitamin E must be considered as potentially toxic.