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Targeting the Inflammasome in Cardiovascular Disease

Maria Belland Olsen1, Ida Gregersen1, Øystein Sandanger1,2

  • 1Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.

JACC. Basic to Translational Science
|February 7, 2022
PubMed

Keywords:
ACS, acute coronary syndromeAIM2, absent in melanoma 2ASC, apoptosis associated speck-like proteinATP, adenosine triphosphateCAD, coronary artery diseaseCRP, C-reactive proteinCVD, cardiovascular diseaseDAMP, damage associated molecular patternGSDMD, gasdermin-DGSDMD-NT, gasdermin-D N-terminalHF, heart failureHFpEF, HF with preserved ejection fractionHFrEF, HF with reduced ejection fractionIL, interleukinIL-1LDL, low-density lipoproteinLV, left ventricularLVEF, left ventricular ejection fractionMI, myocardial infarctionNF-κB, nuclear factor κBNLR, NOD-like receptorNLRP3NLRP3, NOD-like receptor family pyrin domain containing 3NOD, nucleotide-binding oligomerization domainPRR, pattern recognition receptorSTEMI, ST-elevation myocardial infarctionTLR, toll-like receptoratherosclerosiscardiovascular diseaseheart failureinflammasome

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