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Published on: May 23, 2025
[Exploration on acupuncture regulation pathways based on neurovascular coupling].
Yun Liu1, Zhi Yu1, Jin-Feng Jiang1
1Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Acupuncture research can be advanced by studying neurovascular coupling, the interaction between nerves and blood vessels. This interaction is key to how acupuncture signals are processed and how it affects organs.
Area of Science:
- Physiology
- Neuroscience
- Integrative Medicine
Background:
- Acupuncture is recognized for its ability to modulate nerve and blood vessel functions.
- Understanding the physiological interplay between neural and vascular systems is crucial.
Purpose of the Study:
- To explore the physiological significance of neurovascular coupling in relation to acupuncture.
- To propose neurovascular coupling as a framework for acupuncture research.
- To investigate the role of neurovascular coupling in acupuncture's mechanisms of action.
Main Methods:
- Conceptual analysis of existing literature on neurovascular coupling and acupuncture.
- Discussion of the potential involvement of neurovascular coupling in acupuncture signal processing.
- Proposal of research directions based on tissue-specific neurovascular coupling.
Main Results:
- Neurovascular coupling is proposed to be involved in three critical stages of acupuncture: peripheral signal afference, central integration, and target organ regulation.
- Differences in neurovascular coupling expression across tissues suggest varying acupoint efficacies.
Conclusions:
- Neurovascular coupling offers a promising research avenue for understanding acupuncture's physiological effects.
- Investigating acupoint-specific neurovascular coupling can elucidate differential treatment outcomes.
- Stimulation method-dependent neurovascular coupling warrants further study for optimizing acupuncture therapies.
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