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Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions
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An interesting finding: What is the relation between aortic enlargement and COVID-19?

Macit Bitargil1, Tolga Demir1, Hakkı Kürşat Çetin1

  • 1Department of Cardiovascular Surgery, Şişli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey.

Vascular
|February 7, 2022
PubMed

Insights

COVID-19 patients had larger ascending aorta diameters compared to COVID-19-free individuals. This study identified COVID-19, age, and coronary artery disease as key factors influencing aortic enlargement.

Area of Science:

  • Cardiovascular Research
  • Infectious Diseases
  • Radiology

Background:

  • Ascending aorta diameter assessment in COVID-19 patients.
  • Comparison with COVID-19-free individuals in a pandemic hospital setting.

Purpose of the Study:

  • To compare ascending aorta diameters between COVID-19 positive and negative patients.
  • To identify risk factors associated with aortic enlargement in COVID-19 patients.

Main Methods:

  • Case-control study analyzing medical records and thorax tomographies.
  • Measurement of ascending aorta diameter via tomography.
  • Multivariate regression analysis for risk factors of aortic enlargement.

Main Results:

  • 156 patients reviewed (104 COVID-19 positive, 52 negative).
  • Statistically significant difference in mean aortic diameter (39 mm vs. 32.5 mm, p=0.01).
  • COVID-19, age, and coronary artery disease identified as significant factors for aortic enlargement (p<0.05).

Conclusions:

  • COVID-19 patients exhibit larger mean ascending aorta diameters than non-COVID-19 patients.
  • COVID-19 is the leading factor, alongside age and coronary artery disease, influencing aortic dimensions.
Abstract

Keywords:
AortaAortic enlargementCOVID-19

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