Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Selected Data About Geographic Locations01:25

Selected Data About Geographic Locations

83
Geographic Information Systems (GIS) rely on two core types of data: spatial data and attribute data.Spatial DataSpatial data defines the physical location of features within a coordinate system, typically expressed in terms of latitude and longitude. It provides precise positioning for elements like roads, rivers, or buildings.Attribute DataAttribute data complements spatial data by adding descriptive information about these features. For example, a road's spatial data includes its start and...
83
Distribution and Dispersion00:54

Distribution and Dispersion

22.6K
To understand intra-specific interactions in populations, scientists measure the spatial arrangement of species individuals. This geographic arrangement is known as the species distribution or dispersion. Highly territorial species exhibit a uniform distribution pattern, in which individuals are spaced at relatively equal distances from one another. Species that are highly tied to particular resources, such as food or shelter, tend to concentrate around those resources, and thus exhibit a...
22.6K
Diversity of Protists IV01:27

Diversity of Protists IV

258
Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
258
Diversity of Protists II01:27

Diversity of Protists II

248
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
248
Diversity of Protists I01:15

Diversity of Protists I

255
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
255
Diversity of Archaea II01:24

Diversity of Archaea II

122
Archaea, one of the three domains of life, exhibit remarkable diversity and adaptability, thriving in both extreme and moderate environments. Historically, most identified archaea have been classified into two major phyla: Euryarchaeota and Crenarchaeota. However, recent molecular studies have expanded this classification to include three additional phyla: Thaumarchaeota, Nanoarchaeota, and Korarchaeota, each exhibiting unique characteristics and ecological roles.Thaumarchaeota: Mesophiles...
122

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Muscleblind-like proteins dimerize by forming disulfide bonds to regulate alternative splicing and pathogenic RNA foci formation.

Nucleic acids research·2026
Same author

Muscleblind-like proteins dimerize by forming disulfide bonds to regulate alternative splicing and pathogenic RNA foci formation.

bioRxiv : the preprint server for biology·2026
Same author

Suppressive Genetic Interactions Between Haploinsufficient Mitochondrial Genes Encoded in the 22q11.2 Microdeletion Locus Define Brain and Cardiac Phenotypes.

bioRxiv : the preprint server for biology·2026
Same author

Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner.

Molecular biology of the cell·2024
Same author

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.

Nature communications·2023
Same author

Phosphorylation alters FMRP granules and determines their transport or protein synthesis abilities.

bioRxiv : the preprint server for biology·2023
Same journal

Non-canonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy.

eLife·2026
Same journal

Analysis of dendritic input currents during place field dynamics.

eLife·2026
Same journal

TopoMetry systematically learns and evaluates the latent geometry of single-cell data.

eLife·2026
Same journal

Navigating the path: Advice to physician-scientists on choosing a clinical specialty.

eLife·2026
Same journal

Neural activity profiles reveal overlapping, intermingled subpopulations spanning area borders in mouse sensorimotor cortex.

eLife·2026
Same journal

The exquisite mechanics of a tsetse bite.

eLife·2026
See all related articles

Related Experiment Video

Updated: Oct 4, 2025

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
09:55

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology

Published on: September 28, 2022

1.8K

Diversity on location.

Young J Yoon1, Gary J Bassell2

  • 1Department of Neuroscience, Albert Einstein College of Medicine, New York, United States.

Elife
|February 7, 2022
PubMed
Summary
This summary is machine-generated.

The Fragile X mental retardation protein (FMRP) controls the production of proteins at synapses and in the nucleus of neurons. This regulation is crucial for proper neuronal function.

Keywords:
FMRPRNA-binding proteinsfragile x syndromegeneticsgenomicslocal translationmRNA localizationmouseneurosciencesynaptic plasticity

More Related Videos

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations
07:40

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations

Published on: October 29, 2016

11.2K
Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

21.2K

Related Experiment Videos

Last Updated: Oct 4, 2025

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
09:55

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology

Published on: September 28, 2022

1.8K
Monitoring Spatial Segregation in Surface Colonizing Microbial Populations
07:40

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations

Published on: October 29, 2016

11.2K
Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

21.2K

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Genetics

Background:

  • The Fragile X mental retardation protein (FMRP) is a key regulator of gene expression in the brain.
  • Dysregulation of FMRP is associated with neurodevelopmental disorders, including Fragile X syndrome.

Purpose of the Study:

  • To investigate the role of FMRP in protein synthesis within distinct neuronal compartments.
  • To understand how FMRP influences synaptic and nuclear protein production.

Main Methods:

  • Utilized cell-specific RNA sequencing and proteomic analysis.
  • Employed techniques to track protein synthesis in real-time within neurons.

Main Results:

  • FMRP was found to directly regulate the translation of specific mRNAs in both synaptic and nuclear fractions.
  • Identified distinct sets of proteins synthesized under FMRP control in each compartment.

Conclusions:

  • FMRP acts as a critical nexus for coordinating protein synthesis across different neuronal locations.
  • Understanding FMRP's compartmental regulation provides insights into neuronal development and disease mechanisms.