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Updated: Oct 4, 2025

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Traumatic Peripheral Nerve Injury in Mice
Published on: March 25, 2022
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Gunshot-related lower extremity nerve injuries
Hayden P Baker1, Andrew J Straszewski2, James S Dahm2
1Department of Orthopaedic Surgery, The University of Chicago, 5758 S. Maryland Avenue, Dept. 4B, Chicago, IL, 60637, USA. hpbaker65@gmail.com.
Summary
Ballistic trauma to the lower extremities frequently causes nerve injuries, with many patients experiencing full neurologic recovery. Vascular injury increases the risk of nerve damage in these cases.
Area of Science:
- Orthopedic Trauma Surgery
- Neurology
- Vascular Surgery
Background:
- Ballistic trauma to the lower extremities presents a significant challenge in trauma care.
- Nerve injuries are a common complication, impacting patient outcomes.
- Understanding the frequency and recovery patterns of these injuries is crucial.
Approach:
- Retrospective cohort study of patients over 16 years old with lower extremity ballistic trauma.
- Analysis of institutional trauma database from a level 1 trauma academic medical center.
- Inclusion of all identified patients presenting between May 2018 and May 2019.
Key Points:
- 14% of lower extremity ballistic trauma cases involved nerve injuries.
- 73% of patients with nerve injuries achieved complete recovery.
- Vascular injury was present in 38% of patients with nerve injuries, compared to 3% without.
Conclusions:
- Lower extremity nerve injuries are common in ballistic trauma.
- Vascular injury is a significant risk factor for neurologic deficits.
- High index of suspicion for vascular injury is recommended in patients with ballistic lower extremity nerve palsy.
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