Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

50
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
50
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

33
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
33
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

40
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
40
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

67
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
67
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

38
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
38
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

60
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
60

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute kidney injury: incidence and quality of care in patients with type 2 diabetes.

Clinical kidney journal·2026
Same author

Type A Aortic Dissection of the Donor Aorta After Heart Transplantation.

Annals of thoracic surgery short reports·2026
Same author

Cardiac computed tomography-derived fat attenuation index in coronary vasculitis: inflammation development over a year.

European heart journal. Case reports·2025
Same author

Allopurinol, gout, and cardiovascular risk.

European journal of preventive cardiology·2025
Same author

Response commentary: the effect of colchicine on coagulation in patients with chronic coronary disease who use vitamin K antagonists.

European journal of clinical pharmacology·2025
Same author

Colchicine and Longitudinal Dynamics of Clonal Hematopoiesis: An Exploratory Substudy of the LoDoCo2 Trial.

Journal of the American College of Cardiology·2025

Related Experiment Video

Updated: Oct 4, 2025

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.0K

[Non-bacterial thrombotic endocarditis].

Myrthe C van der Burg1, Jan-Willem Balder2, Joop J G van den Brand3

  • 1St. Antonius Ziekenhuis, afdeling Longgeneeskunde, Nieuwegein.

Nederlands Tijdschrift Voor Geneeskunde
|February 7, 2022
PubMed
Summary

Non-bacterial thrombotic endocarditis (NBTE), a rare condition causing sterile heart valve deposits, often presents with systemic embolisms in cancer or autoimmune patients. Early diagnosis and anticoagulation are key to managing this condition.

More Related Videos

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

16.0K
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

11.9K

Related Experiment Videos

Last Updated: Oct 4, 2025

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.0K
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

16.0K
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

11.9K

Area of Science:

  • Cardiology
  • Hematology
  • Oncology

Background:

  • Non-bacterial thrombotic endocarditis (NBTE), or non-infective endocarditis, involves sterile fibrin and platelet deposits on heart valves.
  • NBTE is frequently associated with advanced malignancies, autoimmune disorders, and hypercoagulable states.
  • Patients may be asymptomatic, with clinical signs arising from multifocal systemic embolisms.

Purpose of the Study:

  • To highlight the importance of considering NBTE in the differential diagnosis of systemic embolisms.
  • To present two clinical cases illustrating NBTE in patients with malignancies and autoimmune disorders.

Main Methods:

  • Review of clinical presentations, laboratory tests, and imaging (echocardiography) for NBTE diagnosis.
  • Discussion of therapeutic strategies including anticoagulation and management of underlying conditions.

Main Results:

  • Systemic embolisms in various organs (brain, spleen, kidney, skin, extremities) are the primary clinical manifestations.
  • Diagnosis can be challenging, often relying on clinical suspicion supported by imaging and exclusion of infectious endocarditis.

Conclusions:

  • NBTE should be included in the differential diagnosis for patients with systemic embolisms, particularly those with underlying malignancies or autoimmune diseases.
  • Prompt anticoagulation and treatment of the causative condition are crucial for managing NBTE.