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[Coarctation of the aorta as a cause of difficult-to-control hypertension]
Timion A Meijs1,2, Danny A J P van de Sande1, Jesse Peek3
1UMC Utrecht, afd. Cardiologie, Utrecht.
Insights
Coarctation of the aorta (CoA) is a congenital narrowing that can cause resistant hypertension in young adults. Successful stent implantation resolved severe CoA and hypertension in a 25-year-old patient.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Vascular Surgery
Background:
- Coarctation of the aorta (CoA) is a congenital narrowing of the descending aorta.
- It can manifest as resistant hypertension in pediatric and young adult populations.
- Secondary causes are common in pediatric hypertension.
Observation:
- A 25-year-old female presented with a 9-year history of persistent hypertension despite medication.
- A systolic murmur led to cardiology referral, revealing severe CoA with collateral circulation and a bicuspid aortic valve.
- The patient underwent successful stent implantation for the coarctation.
Findings:
- Post-treatment, the patient achieved normotension without antihypertensive medication.
- This case highlights the successful management of severe coarctation of the aorta in a young adult.
- Effective treatment of CoA can resolve associated resistant hypertension.
Implications:
- Early diagnosis and intervention for coarctation of the aorta are critical.
- Treating coarctation can prevent long-term cardiovascular complications.
- This case underscores the importance of considering congenital heart defects in young adults with unexplained hypertension.
Background:
Coarctation of the aorta (CoA) is a congenital narrowing of the proximal descending aorta, which may express itself as resistant hypertension in children and young adults.
Case Description:
A 25-year old female is known with hypertension for 9 years. Due to persistent hypertension despite telmisartan and amlodipine, she is referred to the outpatient clinic internal medicine, where a systolic murmur is heard. Consequently, she is referred to the cardiologist, who identifies a well-functioning bicuspid aortic valve and a severe CoA with extensive collateral circulation. The CoA is treated by stent implantation. After 7 months, the patient is normotensive without any antihypertensive medication.
Conclusion:
Hypertension in children and young adults is a rare finding and often has a secondary cause. CoA is characterized by a combination of hypertension and a systolic blood pressure gradient between upper and lower extremities. Early diagnosis and treatment are crucial to avoid late cardiovascular complications.
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