Neutrally charged nanosilver antimicrobial effects: A surface thermodynamic perspective
Yudi Wu1, Clayton J Clark1, Chen Lin2
1Department of Civil and Environmental Engineering, FAMU-FSU College of Engineering, Tallahassee, FL 32310, USA.
Colloids and Surfaces. B, Biointerfaces
|February 8, 2022
Summary
Smaller nanosilver particles (AgNP) exhibit enhanced antimicrobial effects due to increased surface area, leading to greater silver ion release and stronger bacterial attachment. This study quantifies AgNP-bacteria interactions to understand size-dependent antimicrobial activity.
Area of Science:
- Nanotechnology
- Microbiology
- Materials Science
Background:
- Nanosilver (AgNP) possesses a large surface area, facilitating interactions with bacteria and silver ion release, crucial for its antimicrobial properties.
- The antimicrobial efficacy of AgNPs is significantly influenced by their size, with smaller particles demonstrating superior activity.
Purpose of the Study:
- To investigate the dynamic interactions between different-sized AgNPs and bacteria in aqueous media.
- To bridge the gap between understanding AgNP antimicrobial effects and their subsequent attachment to bacterial surfaces.
Main Methods:
- Quantification of AgNP-AgNP and AgNP-bacteria interactions using Derjaguin-Landau-Verwey-Overbeek (DLVO) theory and surface chemistry principles.
- Analysis of AgNP aggregation, AgNP attachment to bacteria, and resulting antimicrobial effects.
Main Results:
- Smaller AgNPs exhibit enhanced antimicrobial effects, attributed to larger surface areas, increased silver ion release, and stronger bacterial attachment.
- AgNP size is a critical factor determining both attachment to bacteria and overall antimicrobial effectiveness.
Conclusions:
- AgNP size dictates the interplay between particle aggregation, bacterial attachment, and antimicrobial activity.
- Understanding these size-dependent interactions is essential for optimizing the use of nanosilver as an antimicrobial agent.
Keywords:
And surface thermodynamicsDLVO theoryMICNanosilver aggregationNanosilver attachmentRhamnolipidMore Related Videos
11:52Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
3.3K
07:40Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles
Published on: June 2, 2017
15.2K
Related Concept Videos
01:09Colloidal precipitates
836
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
836
01:18Surface Membrane Barriers
1.6K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.6K
03:45Formation of Complex Ions
24.2K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
24.2K
01:28Antimicrobial Effectiveness
278
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
278