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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

947
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
741
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

874
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Glaucoma Cascade Screening in a High Risk Afro-Caribbean Haitian Population: A Pilot Study.

Ta C Chang1, Linda Celestin1, Elizabeth A Hodapp1

  • 1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL.

Journal of Glaucoma
|February 8, 2022
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Summary

Glaucoma cascade screening in relatives of young Haitian patients identified a high rate of undiagnosed glaucoma. Enhancing provider recruitment and public awareness could improve participation in future screening efforts.

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Area of Science:

  • Ophthalmology
  • Genetics
  • Public Health

Background:

  • Juvenile open-angle glaucoma (JOAG) in Haitian populations necessitates understanding familial risk.
  • Cascade screening in first-degree relatives (FDRs) is a strategy to identify at-risk individuals.

Purpose of the Study:

  • To assess the effectiveness of glaucoma cascade screening in FDRs of Haitian JOAG patients.
  • To determine the prevalence of manifest and suspected glaucoma within this at-risk group.

Main Methods:

  • Identified index patients with JOAG and their FDRs in South Florida.
  • Invited FDRs for free glaucoma screening, including comprehensive eye exams, gonioscopy, visual field testing, and OCT.
  • Collected and analyzed FDR characteristics and clinical findings.

Main Results:

  • Of 77 invited FDRs, 26 (33.8%) participated.
  • Screening identified 2 (7.7%) with manifest glaucoma and 6 (23.1%) with suspected glaucoma.
  • FDRs with manifest glaucoma showed poorer visual acuity and thinner retinal nerve fiber layers.

Conclusions:

  • Glaucoma cascade screening yielded a 30.8% diagnosis rate for suspected or manifest glaucoma in FDRs of Haitian JOAG patients.
  • Provider-initiated recruitment and public education are crucial for increasing screening participation.
  • Targeted screening can identify glaucoma early in high-risk family members.