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Aseptic meningitis as initial manifestation of systemic lupus erythematosus: Case series
Lay Hock Cheok1, Wendy Wan Hui Lee2, Wee Mee Cheng1
1Department of Internal Medicine, Ministry of Health, 69906Miri Hospital, Miri, Malaysia.
Abstract:
Aseptic meningitis is a rare presentation of systemic lupus erythematosus (SLE). High index of suspicion is crucial when there is suboptimal response to the initial standard meningitis treatment and presence of connective tissue disease symptoms. We report 3 cases of aseptic meningitis as the main initial presentation of SLE. The diagnosis of SLE as the underlying cause of the aseptic meningitis was supported by the clinical, laboratory and radiological findings. All patients showed good response after treated with immunosuppressant therapy.
Insights
Aseptic meningitis can be an initial sign of systemic lupus erythematosus (SLE). Prompt diagnosis and immunosuppressant therapy are key for patients presenting with this rare SLE manifestation.
Area of Science:
- Rheumatology
- Neurology
- Immunology
Background:
- Aseptic meningitis is an uncommon initial presentation of systemic lupus erythematosus (SLE).
- A high index of suspicion is vital for patients with suboptimal response to standard meningitis treatment and connective tissue disease symptoms.
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