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Updated: Oct 4, 2025

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
Development and evaluation of safety and effectiveness of novel cancer screening tests for routine clinical use with
Chyke A Doubeni1,2,3,4, Yan Kwan Lau1,2,3, Jennifer S Lin5
1Center for Health Equity and Community Engagement Research, Mayo Clinic, Rochester, Minnesota.
Abstract:
Multicancer screening is a promising approach to improving the detection of preclinical disease, but current technologies have limited ability to identify precursor or early stage lesions, and approaches for developing the evidentiary chain are unclear. Frameworks to enable development and evaluation from discovery through evidence of clinical effectiveness are discussed.
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