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Updated: Oct 4, 2025
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Single Cell Collection of Trophoblast Cells in Peri-implantation Stage Human Embryos
Published on: June 12, 2020
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Elucidating the behavior of trophectoderm derivatives in mouse implantation
Aidan H Terhune1, Jianping Fu2
1Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Developmental Cell
|February 8, 2022
Abstract:
Studying mammalian implantation in utero is difficult, but many in vitro models of peri-implantation development lack contributions from extra-embryonic tissues. Two recently published Developmental Cell papers present biomimetic systems for culturing peri-implantation mouse blastocysts ex vivo. These papers reveal dynamics and developmental impacts of two essential trophectoderm derivatives: extra-embryonic ectoderm and trophoblast.
