Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimizing functional connectivity scanning conditions for predicting autistic traits.

Nature. Mental health·2026
Same author

Transdiagnostic similarities and distinctions in brain networks associated with autistic social impairments: a prospective cohort study.

Molecular autism·2025
Same author

Charting the path in rodent functional neuroimaging.

Imaging neuroscience (Cambridge, Mass.)·2025
Same author

Multimodal identification of the mouse brain using simultaneous Ca<sup>2+</sup> imaging and fMRI.

Communications biology·2025
Same author

PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors.

Nature neuroscience·2025
Same author

Optimizing functional connectivity scanning conditions for predicting autistic traits.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: Oct 4, 2025

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
11:57

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging

Published on: February 24, 2021

10.6K

Consciousness: Mapping the awake mouse brain.

Evelyn M R Lake1

  • 1Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.

Current Biology : CB
|February 8, 2022
PubMed
Summary
This summary is machine-generated.

Consciousness in the brain shows a conserved pattern of activity. This study reveals how spontaneous brain activity in mice changes with wakefulness using functional magnetic resonance imaging.

More Related Videos

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents
14:02

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

Published on: June 29, 2014

23.0K
Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake Mice
08:26

Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake Mice

Published on: August 23, 2022

2.5K

Related Experiment Videos

Last Updated: Oct 4, 2025

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
11:57

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging

Published on: February 24, 2021

10.6K
Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents
14:02

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

Published on: June 29, 2014

23.0K
Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake Mice
08:26

Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake Mice

Published on: August 23, 2022

2.5K

Area of Science:

  • Neuroscience
  • Cognitive Science

Background:

  • Brain activity exhibits a unique spatiotemporal signature during consciousness.
  • This signature is evolutionarily conserved across species.
  • Understanding brain activity dynamics is crucial for consciousness research.

Purpose of the Study:

  • To investigate the reconfiguration of spontaneous brain activity during changes in consciousness.
  • To examine the role of wakefulness in modulating brain activity patterns.
  • To explore the conserved nature of brain activity signatures.

Main Methods:

  • Utilized functional magnetic resonance imaging (fMRI) in a murine model.
  • Analyzed spontaneous brain activity patterns.
  • Compared brain activity during different states of wakefulness.

Main Results:

  • Demonstrated significant reconfigurations in spontaneous brain activity with wakefulness.
  • Identified specific changes in the spatiotemporal dynamics of neural activity.
  • Provided evidence for the conserved nature of these activity patterns.

Conclusions:

  • Spontaneous brain activity undergoes dynamic changes related to the state of consciousness.
  • Wakefulness plays a critical role in shaping these neural dynamics.
  • The findings support the conserved spatiotemporal signature of brain activity during consciousness.