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Updated: Oct 4, 2025

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
Published on: June 5, 2020
Impact of information intervention on stochastic hepatitis B model and its variable-order fractional network
Anwarud Din1, Yongjin Li1, Abdullahi Yusuf2,3
1Department of Mathematics, Sun Yat-sen University, Guangzhou, 510275 People's Republic of China.
Abstract:
This paper aims at analyzing the dynamical behavior of a SIR hepatitis B epidemic stochastic model via a novel approach by incorporating the effect of information interventions and random perturbations. Initially, we demonstrate the positivity and global existence of the solutions. Afterward, we derive the stochastic threshold parameter , followed by the fact that this number concludes the transmission of hepatitis B from the population. By increasing the intensity of noise, we get less than one, inferring that ultimately hepatitis B will lapse. While decreasing the intensity of noise to a sufficient level, we have . For the case , adequate results for the presence of stationary distribution are achieved, showing the prevalence of hepatitis B. The present study also involves the derivation of the necessary conditions for the persistence of the epidemic. Finally, the main theoretical solutions are plotted through simulations. Discussion on theoretical and numerical results shows that utilizing random perturbations and information interventions have a pronounced impact on the syndrome's dynamics. Furthermore, since most communities interact with each other, and the disease spread rate is affected by this factor, a new variable-order fractional network of the stochastic hepatitis B model is offered. Subsequently, this study will provide a robust theoretical basis for comprehending worldwide SIR stochastic and variable-order fractional network-related case studies.
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