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Logical Analysis of Multiple Single-Nucleotide-Polymorphisms with Programmable DNA Molecular Computation for Clinical

Chao Zhang1, Tingting Zheng1, Qian Ma1

  • 1Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, State Key Laboratory of Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.

Angewandte Chemie (International Ed. in English)
|February 9, 2022
PubMed
Summary

This study introduces a DNA computing method for analyzing complex single-nucleotide-polymorphism (SNP) combinations, enabling rapid and accurate blood group genotype identification for clinical diagnosis and personalized medicine.

Keywords:
Blood GroupDNA Molecular ComputationGenotypingLogical AnalysisSingle Nucleotide Polymorphism

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