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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
212
Peripheral access size evaluation in transfemoral transcatheter aortic valve replacement
Irbaz Hameed1, Christian T Oakley2, N U F Hameed2
1Division of Cardiothoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
Journal of Cardiac Surgery
|February 9, 2022
Summary
Most patients screened for transcatheter aortic valve replacement (TAVR) have adequate peripheral vessel sizes for the procedure. Pre-TAVR computed tomography angiography (CTA) may be indicated based on individual patient risk factors and vessel characteristics.
Area of Science:
- Cardiovascular Imaging
- Interventional Cardiology
- Vascular Medicine
Background:
- Peripheral access vessel dimensions are crucial for transcatheter aortic valve replacement (TAVR) procedures.
- Assessing these dimensions can inform the necessity of pre-TAVR computed tomography angiography (CTA).
Purpose of the Study:
- To determine peripheral access vessel sizes in patients screened for TAVR.
- To identify patient characteristics associated with these vessel dimensions.
Main Methods:
- Retrospective review of 1049 patients screened for TAVR (April 2012-March 2019).
- Contrast-enhanced CTA used to measure minimal luminal diameters (MLDs) of transfemoral access vessels.
- Statistical analyses included t-tests and regression to identify factors associated with MLD.
Main Results:
- Mean femoral artery MLDs were 7.73 mm (right) and 7.68 mm (left).
- Male sex and higher BMI were associated with larger MLDs.
- Conditions like peripheral vascular disease, hypertension, and smoking were inversely associated with MLD.
Conclusions:
- Most TAVR-screened patients possess peripheral vessel sizes adequate for current transcatheter heart valves.
- Clinical judgment of patient risk factors is essential for deciding on pre-TAVR CTA.
- Further research, including randomized controlled trials, is needed to compare outcomes with and without preoperative CTA.
Keywords:
cardiovascular imagingcomputed tomography angiographyilliofemoral arteriesperipheral accesstranscatheter aortic valve replacement
