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Updated: Oct 4, 2025

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[Blood pressure control in good hands with the general practicioner?]
1Uitvoeringsinstituut Werknemersverzekeringen (UWV), afd. Sociaal-Medische Zaken, Rotterdam.
Eighty-seven percent of patients with uncontrolled hypertension received no treatment changes, a phenomenon termed therapeutic inertia. Factors like older age and diabetes influenced this, but overall hypertension management in general practice is considered appropriate.
Area of Science:
- General Practice
- Cardiology
- Public Health
Background:
- Uncontrolled hypertension remains a significant public health concern.
- Therapeutic inertia, the lack of treatment adjustment for uncontrolled hypertension, is prevalent in general practice.
- Factors influencing therapeutic inertia require further investigation.
Purpose of the Study:
- To analyze the prevalence and associated factors of therapeutic inertia in general practice.
- To discuss the appropriateness of therapeutic inertia in the context of shared decision-making and evolving guidelines.
- To examine the role of healthcare professionals, including practice nurses and general practitioners, in hypertension management.
Main Methods:
- Retrospective analysis of a large cohort (n=6400) of patients with uncontrolled hypertension in general practice.
- Statistical analysis to identify factors associated with therapeutic inertia.
- Qualitative discussion on clinical decision-making and guideline implications.
Main Results:
- No therapeutic action was taken during follow-up in 87% of patients with uncontrolled hypertension.
- Older age, lower blood pressure readings, and diabetes were associated with increased therapeutic inertia.
- Specific focus on unjustified inertia in hypertensive diabetic patients was highlighted.
Conclusions:
- While therapeutic inertia is observed, its appropriateness in shared decision-making warrants consideration.
- The role of practice nurses and general practitioner supervision in hypertension management is crucial.
- Despite identified inertia, the overall management of hypertension in general practice is deemed appropriate.
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