Related Experiment Video
Updated: Oct 4, 2025
Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
[Current status of chondrosarcoma in a reference center]
M A Clara-Altamirano1, D Y García-Ortega1, M Núñez-González2
1Departamento de Piel y Partes Blandas Instituto Nacional de Cancerología. Ciudad de México. México.
Introduction:
Chondrosarcoma is the second most frequent primary malignant bone tumor, is characterized by the formation of a chondroid matrix, is more frequent in advanced ages and its prognosis is directly related to the histological subtype and tumor grade. The objective of this article is to present the demographic and treatment profile in a reference center.
Material And Methods:
A retrospective, descriptive, observational, analytical cohort-type study was conducted in a reference center between January 1, 2005 and December 31, 2019, the demographic variables were analyzed and contrasted with the outcome variables that were overall survival and disease-free period.
Results:
85 patients were included, the mean age of presentation was 43.3 years, the clinical stage at the time of presentation was mostly IIa and IIb covering 54.1%. 35 patients had metastases with clinical stage IV. The main site of metastasis was the lung in 32 patients (37.6%). Thirty-six patients (42.3%) had specific mortality. 35 patients (41.2%) died as a result of metastatic disease to lung or other organs, one patient died from direct extension of the tumor in the cervical spine.
Conclusion:
The important prognostic factors found in our series that influence global survival are: the presence of metastases and axial localization.
