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Intensive care unit management of uncomplicated type B aortic dissection in relation to treatment period: a
Chul Ho Lee1, Jae Seok Jang1, Jun Woo Cho1
1Department of Thoracic and Cardiovascular Surgery, Daegu Catholic University School of Medicine, Daegu, Korea.
Insights
Intensive care unit (ICU) management is not essential for uncomplicated acute type B aortic dissection (ATBAD). Calcium channel blockers may reduce aortic events during follow-up for ATBAD patients.
Area of Science:
- Cardiovascular Medicine
- Thoracic Surgery
- Critical Care Medicine
Background:
- Medical therapy is standard for acute type B aortic dissection (ATBAD).
- Evidence supporting intensive care unit (ICU) management for uncomplicated ATBAD is limited.
- The necessity of ICU treatment for uncomplicated ATBAD requires further investigation.
Purpose of the Study:
- To evaluate the impact of ICU treatment duration on outcomes in patients with uncomplicated ATBAD.
- To compare the incidence of complications and long-term survival between patients with short-term versus long-term ICU stays.
Main Methods:
- Retrospective study of 55 patients with uncomplicated ATBAD treated between 2010 and 2020.
- Patients categorized into long-term ICU stay (LIS) and short-term ICU stay (SIS) groups based on a 48-hour cutoff.
- Comparison of pneumonia, delirium, aortic events, mortality, and survival rates between LIS and SIS groups.
Main Results:
- No statistically significant differences in pneumonia or delirium rates between LIS and SIS groups.
- Similar 1, 3, and 5-year survival rates for both LIS and SIS groups (p=0.102).
- Multivariate analysis indicated calcium channel blocker use is associated with a lower risk of aortic events.
Conclusions:
- Extended ICU stays are likely unnecessary for uncomplicated ATBAD.
- Active use of antihypertensive medications, specifically calcium channel blockers, may be beneficial during ATBAD follow-up.
- Further research may refine management protocols for uncomplicated ATBAD.
Backgruound:
Medical therapy is the standard treatment for uncomplicated acute type B aortic dissection (ATBAD), but there is little evidence of the need for intensive care unit (ICU) management. Therefore, we aimed to investigate the effects of ICU treatment on uncomplicated ATBAD.
Methods:
We retrospectively studied patients with uncomplicated ATBAD who were medically treated between January 2010 and July 2020. Patients were divided into long-term ICU stay (LIS) and short-term ICU stay (SIS) groups, according to a 48-hour cutoff of ICU stay duration. The incidence of pneumonia and delirium, rate of aortic events, hospital mortality, and survival rate were compared.
Results:
Fifty-five patients were treated for uncomplicated ATBAD (n=26 for LIS and n=29 for SIS). The incidence of pneumonia (7.7% vs. 3.6%) and delirium (34.6% vs. 14.3%) was higher in the LIS group than in the SIS group, but the differences were not statistically significant. The survival rates at 1, 3, and 5 years were not different between the two groups (LIS: 96.2%, 88.0%, and 54.2% vs. SIS: 96.4%, 92.2%, and 75.5%, respectively; p=0.102). Multivariate Cox regression analysis for aortic events showed that using a calcium channel blocker lowered the risk of aortic events.
Conclusion:
Long-term ICU treatment is unlikely to be necessary for the treatment of uncomplicated ATBAD. Active use of antihypertensive agents, such as calcium channel blockers, may be needed during the follow-up period.
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