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Related Experiment Video

Updated: Oct 4, 2025

Sit-to-stand-and-walk from 120% Knee Height: A Novel Approach to Assess Dynamic Postural Control Independent of Lead-limb

Sit-to-stand-and-walk from 120% Knee Height: A Novel Approach to Assess Dynamic Postural Control Independent of Lead-limb

Published on: August 30, 2016

Walking instead of standing.

Florian Junge¹, Wolfgang Konschake¹, Hermann Haase¹

¹Department of Dermatology, University Medicine Greifswald, Germany.

VASA. Zeitschrift Fur Gefasskrankheiten

|February 10, 2022

Summary

This summary is machine-generated.

Prolonged standing causes lower leg volume increase and discomfort. This study found a direct link between leg swelling and the sensation of discomfort, suggesting a causal relationship in healthy individuals.

Keywords:

Leg edema healthy subjects leg complaints orthostasis

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Last Updated: Oct 4, 2025

Sit-to-stand-and-walk from 120% Knee Height: A Novel Approach to Assess Dynamic Postural Control Independent of Lead-limb

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Area of Science:

Physiology
Vascular Biology
Human Factors

Background:

Lower leg discomfort is prevalent, particularly in occupations requiring prolonged standing or sitting.
The relationship between lower leg volume increase and discomfort sensation remains unclear.

Purpose of the Study:

To investigate the temporal relationship between lower leg volume changes and the onset of discomfort.
To determine if increased leg volume causally influences discomfort and the urge to move.

Main Methods:

A nonrandomized controlled study involving a 15-minute standing period.
Quantification of lower leg volume changes and subjective discomfort using a numerical rating scale (NRS).
Correlation and linear mixed-effects modeling to assess relationships between volume and symptoms.

Main Results:

Lower leg volume increased significantly (average 63 ml, p<0.001) during standing.
Discomfort and urge to move sensations increased substantially on the NRS (p<0.001).
Significant correlations found between leg volume increase and discomfort (9/15 subjects) and urge to move (11/15 subjects).

Conclusions:

Prolonged standing without movement induces lower leg volume increase and discomfort in healthy individuals.
Linear mixed-effects models indicate a causal relationship between leg volume changes and symptom perception.