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Single-Atom Nanozymes for Biomedical Applications: Recent Advances and Challenges
Minglu Tang1, Jingqi Li1, Xinda Cai1
1Key Laboratory of Forest Plant Ecology, Ministry of Education, Engineering Research Center of Forest Bio-Preparation, College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin, 150040, P. R. China.
Chemistry, an Asian Journal
|February 10, 2022
Summary
Single-atom nanozymes (SAzymes) offer enhanced catalytic efficiency over traditional nanozymes. This review explores their mechanisms, applications in biomedical sensing and therapy, and future prospects.
Area of Science:
- Nanotechnology
- Catalysis
- Biomedical applications
Background:
- Nanozymes combine enzyme-like catalytic activity with nanomaterial properties, offering stability and ease of preparation.
- Conventional nanozymes face limitations in size and catalytic efficiency for advanced applications.
- Single-atom nanozymes (SAzymes) utilize uniformly distributed single atoms as active sites for superior catalytic performance.
Purpose of the Study:
- To review activity improvement schemes and catalytic mechanisms of SAzymes.
- To highlight recent advancements in SAzymes for biomedical sensing and therapy.
- To discuss challenges and future directions for SAzyme development.
Main Methods:
- Literature review of SAzyme research.
- Analysis of catalytic mechanisms and activity enhancement strategies.
- Synthesis of recent findings in biomedical sensing and therapy applications.
Main Results:
- SAzymes demonstrate significantly higher catalytic efficiency compared to conventional nanozymes.
- Single atoms as catalytic sites effectively overcome limitations of traditional nanozymes.
- SAzymes show promising progress in biomedical sensing and therapeutic applications.
Conclusions:
- SAzymes represent a significant advancement in nanozyme technology.
- Further research into activity improvement and mechanisms will drive SAzyme innovation.
- SAzymes hold great potential for future biomedical and industrial applications.
