Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Necrosis01:16

Necrosis

4.9K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
4.9K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

4.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.4K
Burn Injuries01:22

Burn Injuries

3.1K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
3.1K
Tissue Transplantation01:24

Tissue Transplantation

551
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
551

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physiological studies of the deep-water coral Madrepora oculata incubated at different temperatures and hydrostatic pressures.

The Journal of experimental biology·2026
Same author

Expression of the novel serum biomarker of testicular germ cell tumours miR-371a-3p in serum of pregnant women: a case-control study.

European journal of medical research·2025
Same author

Deletion of Tbc1d4/As160 abrogates cardiac glucose uptake and increases myocardial damage after ischemia/reperfusion.

Cardiovascular diabetology·2023
Same author

[Ambulatory laparoscopic colectomy : First experiences at the CHU of Liège].

Revue medicale de Liege·2021
Same author

Scallop Theorem and Swimming at the Mesoscale.

Physical review letters·2021
Same author

[Enhanced recovery after surgery in colorectal surgery].

Revue medicale de Liege·2020
Same journal

[Nature prescriptions and health promotion : sharing experience from primary care].

Revue medicale de Liege·2026
Same journal

[Eco-health: shared perspectives on primary care practice].

Revue medicale de Liege·2026
Same journal

[The strategic role of primary care in emerging diseases : surveillance, research, and preparedness].

Revue medicale de Liege·2026
Same journal

[Environmental impact of medicines and approaches for more eco responsible use].

Revue medicale de Liege·2026
Same journal

[Climate change and skin].

Revue medicale de Liege·2026
Same journal

[From Silent Spring to neuronal silence : pesticides and neurodegenerative diseases].

Revue medicale de Liege·2026
See all related articles

Related Experiment Video

Updated: Oct 4, 2025

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
08:55

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

Published on: August 7, 2018

11.0K

[Soft tissue necrotizing infection].

O Deschaumes1, M Hubert2, P Y Hardy2

  • 1Service des Urgences, CHU, Liège, Belgique.

Revue Medicale De Liege
|February 10, 2022
PubMed
Summary
This summary is machine-generated.

Necrotizing fasciitis and gas gangrene are severe infections requiring prompt treatment. This case highlights challenges in managing these conditions, especially when surgery is not an option.

Keywords:
DebridementDiabetesGas gangreneNecrotizing fasciitis

More Related Videos

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

622
Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

5.3K

Related Experiment Videos

Last Updated: Oct 4, 2025

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
08:55

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

Published on: August 7, 2018

11.0K
A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

622
Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

5.3K

Area of Science:

  • Infectious Diseases
  • Surgical Pathology

Background:

  • Necrotizing fasciitis and gas gangrene are life-threatening infections characterized by rapid progression.
  • Diabetes mellitus is a primary risk factor, increasing susceptibility to these severe soft tissue infections.

Observation:

  • Early multidisciplinary treatment, including surgical intervention, is crucial for survival.
  • Conservative management is associated with a high mortality rate.
  • Diagnostic tools like imaging, lab tests, and bacteriology aid in diagnosis, with definitive diagnosis often occurring intraoperatively.

Findings:

  • A case of a diabetic patient with a traumatic wound developing rapidly progressive necrotizing fasciitis is presented.
  • The extensive acute nature of the infection precluded surgical intervention in this specific case.

Implications:

  • This case underscores the critical role of timely surgical debridement in managing necrotizing fasciitis and gas gangrene.
  • Even with appropriate supportive care, high mortality remains a concern, emphasizing the need for aggressive early treatment strategies.