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DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis

Melissa D Chengalroyen1, Mandy K Mason1, Alessandro Borsellini2

  • 1SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa.

ACS Infectious Diseases
|February 10, 2022
PubMed

Keywords:
DNA damageDNA polymeraseDnaE1Mycobacterium tuberculosisantimicrobial drug discoverynargenicin

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