Related Experiment Video

Updated: Oct 4, 2025

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

11.6K

The Edinburgh Claudication Questionnaire has poor diagnostic accuracy in people with intermittent claudication

Saïd Ibeggazene1,2, Andrew Stirrup1, Sean Pymer1

  • 1Academic Vascular Surgical Unit, 12195Hull York Medical School, Hull, UK.

Vascular
|February 10, 2022
PubMed

Insights

The Edinburgh Claudication Questionnaire (ECQ) showed poor diagnostic performance for screening intermittent claudication. Further research is needed for better diagnostic tools in primary care referrals.

Area of Science:

  • Vascular Medicine
  • Diagnostic Accuracy Studies
  • Primary Care Screening

Background:

  • Screening and diagnosing intermittent claudication presents challenges, often requiring specialist vascular expertise.
  • The Edinburgh Claudication Questionnaire (ECQ) is a tool used for screening suspected intermittent claudication.
  • Investigating the ECQ's diagnostic performance in primary care referrals is crucial.

Purpose of the Study:

  • To evaluate the diagnostic performance of the Edinburgh Claudication Questionnaire (ECQ).
  • To assess the ECQ's utility as a screening tool for intermittent claudication referrals from primary to secondary care.

Main Methods:

  • Prospective study involving 100 primary care referrals for suspected intermittent claudication.
  • Participants completed the ECQ and underwent Ankle-Brachial Pressure Index (ABPI) assessment and treadmill exercise testing.
  • ECQ outcomes were compared against clinical diagnoses of intermittent claudication.

Main Results:

  • The ECQ demonstrated low diagnostic performance with a sensitivity of 46.8% and specificity of 63.2%.
  • The overall accuracy of the ECQ was 53.0%.
  • Combining the ECQ with ABPI results did not improve its diagnostic performance for peripheral artery disease (PAD).

Conclusions:

  • The ECQ exhibited poor diagnostic performance in the studied cohort.
  • The utility of the ECQ for screening and epidemiological surveys is questionable based on current evidence.
  • There is a need for novel, low-resource diagnostic tools for intermittent claudication.
Abstract

Keywords:
Intermittent claudicationdiagnosisperipheral artery disease

More Related Videos

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research08:42

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

Published on: October 22, 2014

27.5K
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

526

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
49
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
539
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
148
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
67
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
44