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Updated: Oct 4, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Shape and boundary-aware multi-branch model for semi-supervised medical image segmentation.

Xiaowei Liu1, Yikun Hu1, Jianguo Chen2

  • 1College of Computer Science and Electronic Engineering, Hunan University, Changsha, 410082, China.

Computers in Biology and Medicine
|February 10, 2022
PubMed
Summary

This study introduces a novel semi-supervised deep learning model for medical image segmentation. The model effectively utilizes limited labeled data and unlabeled data to improve segmentation accuracy and generalization.

Keywords:
Boundary awareMedical images segmentationMulti-branch consistenceSemi-supervised learning

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Area of Science:

  • Medical Imaging
  • Computer Vision
  • Machine Learning

Background:

  • Supervised medical image segmentation requires extensive labeled data, which is often scarce and costly to obtain.
  • Limited labeled data leads to poor model performance, including overfitting and low accuracy in medical image analysis.
  • Existing methods struggle with the labor-intensive nature of medical image annotation.

Purpose of the Study:

  • To develop a novel shape and boundary-aware deep learning model for medical image segmentation.
  • To leverage semi-supervised learning to effectively utilize both labeled and unlabeled data.
  • To enhance segmentation accuracy, especially in boundary regions, by incorporating shape and distance map information.

Main Methods:

  • A V-Net architecture was employed for Pixel-wise Segmentation Map (PSM) and Signed Distance Map (SDM) prediction.
  • Multi-scale features were enhanced around target boundaries using SDM information and a Pyramid Pooling Module (PPM).
  • Task consistency loss was applied to PSM and SDM outputs to effectively mine unlabeled data.

Main Results:

  • The proposed model demonstrated superior performance across three challenging medical image datasets (LA2018, BraTS2019, ISIC2018).
  • The boundary-aware features and SDM integration improved segmentation accuracy, particularly in complex regions.
  • The semi-supervised approach significantly enhanced model generalization compared to purely supervised methods.

Conclusions:

  • The novel semi-supervised model offers a practical and superior solution for medical image segmentation with limited labeled data.
  • Integrating shape and boundary information effectively addresses segmentation challenges in medical imaging.
  • The model's ability to utilize unlabeled data holds significant promise for advancing automated medical image analysis.