Severe varicella in a child immunosuppressed with methotrexate
Letícia Oba Galvão1, Carmelia Matos Santiago Reis1, Natália Lima Alves1
1Dermatology Service, Hospital Regional da Asa Norte, Brasília, DF, Brazil.
Abstract:
Varicella is a common viral infection in childhood and usually has a benign evolution. However, the evolution can be severe in immunosuppressed children. Vaccination can prevent its occurrence and especially the development of severe and/or complicated cases. Methotrexate is a systemic therapeutic option for many inflammatory diseases, and its immunosuppressive action exposes its users to a higher susceptibility to infection. The present report describes a case of severe varicella infection in a child immunosuppressed with methotrexate.
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