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Related Experiment Video

Updated: Oct 4, 2025

Three-Dimensional Shape Modeling and Analysis of Brain Structures
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A review on 3D printing functional brain model.

Roya Samanipour, Hamed Tahmooressi1, Hojatollah Rezaei Nejad2

  • 1Department of Mechanical Engineering, University of British Columbia, Kelowna, British Columbia V1V 1V7, Canada.

Biomicrofluidics
|February 11, 2022
PubMed
Summary
This summary is machine-generated.

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3D bioprinting offers a high-throughput method for creating neural tissue models. Developing suitable neural bioinks is key to advancing this technology for neuroscience research.

Area of Science:

  • Neuroscience
  • Biomaterials Science
  • Tissue Engineering

Background:

  • Modern neuroscience utilizes 3D models for studying neural circuitry, regeneration, and diseases.
  • Various biofabrication methods exist for creating 3D neural tissue models.
  • 3D bioprinting presents a promising high-throughput and high-precision strategy for 3D neural model fabrication.

Purpose of the Study:

  • To review design principles for neural tissue engineering.
  • To explore biomaterials and fundamentals of 3D neural tissue printing.
  • To review advances in 3D bioprinting technologies for neural models.

Main Methods:

  • Literature review of biomaterials for neural bioinks.
  • Analysis of 3D bioprinting technologies for neural tissue fabrication.

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Utilizing 3D Printing Technology to Merge MRI with Histology: A Protocol for Brain Sectioning
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Last Updated: Oct 4, 2025

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  • Comparison of evaluation techniques for 2D and 3D neural models.

    • Main Results:

    • The development of neural bioinks with appropriate printability, gelation, and neural cell compatibility is a primary challenge.
    • A wide array of biomaterials and fundamental principles for 3D neural tissue printing are discussed.
    • Recent advancements in 3D bioprinting technologies specifically for neural models are reviewed.

    Conclusions:

    • 3D bioprinting is a powerful tool for generating complex 3D neural models.
    • Neural bioink development is critical for successful neural tissue engineering via bioprinting.
    • The review provides insights into current techniques for evaluating fabricated neural models.