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Related Experiment Video

Updated: Oct 4, 2025

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

Netarsudil-associated reticular corneal epithelial edema.

Jennifer A Tran¹, Ula V Jurkunas², Jia Yin²

¹Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology, 243 Charles Street, Boston, MA, 02114, USA.

American Journal of Ophthalmology Case Reports

|February 11, 2022

Summary

Topical netarsudil, a Rho-kinase inhibitor, can cause reversible reticular corneal epithelial edema in patients, even those with pre-existing corneal conditions. This condition resolved after discontinuing netarsudil treatment.

Area of Science:

Ophthalmology
Corneal Disease
Pharmacology

Background:

Rho-kinase inhibitors are used to treat glaucoma.
Corneal complications can arise from topical ophthalmic medications.

Keywords:

Corneal edema Honeycomb edema Netarsudil Reticular edema Rhopressa

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Reticular corneal epithelial edema is a specific type of corneal swelling.