Related Experiment Video
Updated: Oct 4, 2025

04:48
Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
Published on: November 22, 2024
462
Netarsudil-associated reticular corneal epithelial edema
Jennifer A Tran1, Ula V Jurkunas2, Jia Yin2
1Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology, 243 Charles Street, Boston, MA, 02114, USA.
American Journal of Ophthalmology Case Reports
|February 11, 2022
Summary
Topical netarsudil, a Rho-kinase inhibitor, can cause reversible reticular corneal epithelial edema in patients, even those with pre-existing corneal conditions. This condition resolved after discontinuing netarsudil treatment.
Area of Science:
- Ophthalmology
- Corneal Disease
- Pharmacology
Background:
- Rho-kinase inhibitors are used to treat glaucoma.
- Corneal complications can arise from topical ophthalmic medications.
- Reticular corneal epithelial edema is a specific type of corneal swelling.

