Related Experiment Video
Updated: Oct 4, 2025

06:20
Author Spotlight: Advancing VRL Diagnosis Using Cell-Free DNA Extraction from Vitreous Humor
Published on: January 12, 2024
2.2K
Secondary vitreoretinal lymphoma with spontaneous regression
Wijak Kongwattananon1,2, Aman Kumar1,3, Jillian Simard4
1National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
American Journal of Ophthalmology Case Reports
|February 11, 2022
Summary
This case study highlights a rare instance of spontaneous regression in vitreoretinal lymphoma (VRL) secondary to diffuse large B-cell lymphoma. The patient experienced two distinct episodes of ocular lymphoma remission without treatment.
Area of Science:
- Ophthalmology
- Hematology
- Oncology
Background:
- Diffuse large B-cell lymphoma can rarely manifest as vitreoretinal lymphoma (VRL).
- VRL requires accurate diagnosis and monitoring for effective management.
- Spontaneous regression of intraocular lymphoma is an exceptionally rare phenomenon.

