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Achromobacter spp. bacteremia outbreak related to contaminated furosemide ampoules

Rajalakshmi Arjun1, Kalpana E John2, Vettakkara Kandy Muhammed Niyas1

  • 1Department of Infectious Diseases, KIMSHEALTH, Thiruvananthapuram, Kerala, India.

Le Infezioni in Medicina
|February 11, 2022
PubMed

Insights

Nosocomial outbreaks caused by contaminated medications, like furosemide ampoules, can be stopped. Identifying the source through investigation and removing the contaminated batch quickly ended this Achromobacter bacteremia outbreak.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Microbiology

Background:

  • Nosocomial outbreaks due to medication contamination pose a global health risk.
  • A rise in Achromobacter spp. bacteremia cases prompted an investigation.

Purpose of the Study:

  • To investigate the source of an Achromobacter spp. bacteremia outbreak.
  • To identify the contaminated medication responsible for the nosocomial outbreak.

Main Methods:

  • Conducted a line listing of cases.
  • Performed environmental sampling to identify contamination sources.
  • Utilized molecular identification for bacterial species analysis.

Main Results:

  • Contaminated furosemide ampoules were identified as the outbreak source.
  • Molecular methods revealed the presence of multiple Achromobacter species.
  • The outbreak was linked to a specific batch of contaminated furosemide.

Conclusions:

  • Prompt identification and withdrawal of contaminated medication are crucial for outbreak control.
  • Medication contamination remains a significant threat in healthcare settings.
  • Molecular techniques aid in understanding complex microbial outbreaks.
Keywords:
Achromobacterbacteremiamedication contaminationnosocomial infectionsoutbreak

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