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Plant-Based Support of Respiratory Health during Viral Outbreaks
Thirumurugan Rathinasabapathy1,2, Lakshmana Prabu Sakthivel3, Slavko Komarnytsky1,2
1Plants for Human Health Institute, North Carolina State University, North Carolina Research Campus, 600 Laureate Way, Kannapolis, North Carolina 28081, United States.
Botanical interventions show promise for supporting respiratory health against viral infections. Further research into plant metabolites may reveal novel therapeutic targets for managing respiratory viral outbreaks.
Area of Science:
- Phytomedicine
- Virology
- Pharmacology
Background:
- Respiratory viruses cause significant global health burdens, with limited pharmaceutical treatments.
- Developing effective interventions for respiratory viral outbreaks remains a challenge.
Purpose of the Study:
- To review botanical interventions for respiratory health.
- To explore the potential of plant-derived compounds in managing respiratory viral infections.
Main Methods:
- Literature review of botanical species with reported respiratory benefits.
- Analysis of proposed mechanisms of action and structure-activity relationships of bioactive compounds.
Main Results:
- Several plant species (e.g., Bupleurum, Glycyrrhiza, Andrographis) have suggested bioactive compounds with explored activity.
- Other species (e.g., Echinacea, Zingiber, Verbascum, Marrubium, Sambucus, Urtica) show potential but require further investigation.
Conclusions:
- Botanical interventions offer a promising avenue for supporting respiratory health.
- Investigating plant metabolites can uncover new therapeutic targets for respiratory viral outbreaks.
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