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Related Experiment Video

Updated: Oct 4, 2025

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DiaNe: A New First-Level Computerized Tool Assessing Memory, Attention, and Visuospatial Processing to Detect Early

Antonella Di Vita1, Francesca Vecchione2,3, Maddalena Boccia2,3

  • 1Department of Human Neurosciences, "Sapienza" University of Rome, Rome, Italy.

Journal of Alzheimer'S Disease : JAD
|February 11, 2022
PubMed
Summary

Early detection of cognitive decline is vital. A new computerized tool, DiaNe (Diagnosis of Neurocognitive disease), aids in identifying preclinical neurocognitive disorders through self-administered tablet tests, offering a sensitive screening method.

Keywords:
AgingAlzheimer’s diseasecomputerized test batterydementiaepisodic memorymild cognitive impairmentneuropsychologyspatial memorysubjective cognitive declineverbal memory

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Area of Science:

  • Neuroscience
  • Gerontology
  • Medical Technology

Background:

  • Early detection of cognitive decay is crucial for managing and potentially preventing dementia progression.
  • Routine neuropsychological examinations are important for identifying early cognitive decline, as many individuals are unaware of their decreasing cognitive efficiency.
  • There is a critical need for a screening tool that is computerized, portable, self-administrable, and sensitive to neurocognitive changes indicative of pathological aging.

Purpose of the Study:

  • To develop a computerized battery for the early, preclinical diagnosis of neurocognitive disease (DiaNe).
  • To create a self-administered tool for autonomous use via a tablet.
  • To provide a sensitive screening method for detecting early signs of cognitive decline.

Main Methods:

  • Developed DiaNe, a computerized battery assessing key cognitive domains (memory, attention, executive functions).
  • Included a detailed assessment of visuospatial memory.
  • Designed for self-administration on a tablet, focusing on accuracy and response time measurements.

Main Results:

  • DiaNe is a novel tool, not merely a digital translation of existing tests.
  • It screens cognitive profiles and monitors them over time.
  • It can detect subtle changes in normal performance suggestive of early neurocognitive disorders.

Conclusions:

  • DiaNe demonstrates concurrent validity, with results comparable to traditional paper-and-pencil neuropsychological tests.
  • DiaNe is proposed as a useful, quick, and economical instrument for monitoring cognitive aging.
  • This tool can aid in the early identification and management of neurocognitive disorders.