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Isolation and Purification of Fungal β-Glucan as an Immunotherapy Strategy for Glioblastoma
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Fungal sugars boost vaccine protection
1Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Abstract:
In this issue of Cell, Borriello et al. show that soluble fungal mannans elicit potent innate immune responses within skin-draining lymph nodes. These can be exploited for effective development of adaptive immune responses against viral glycoproteins, thus enhancing vaccine immunogenicity and protection.
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