Global burden of heart failure: a comprehensive and updated review of epidemiology

Gianluigi Savarese1,2, Peter Moritz Becher1,3, Lars H Lund1,2

  • 1Division of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Cardiovascular Research
|February 12, 2022
PubMed

Insights

Heart failure (HF) affects over 64 million globally, posing a significant public health challenge. Its increasing prevalence, driven by aging populations and better treatments, necessitates updated global burden estimates.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Heart failure (HF) is a critical global health issue with high morbidity, mortality, and economic impact.
  • Over 64 million individuals worldwide are affected by HF, highlighting its substantial burden.
  • While incidence declines in developed nations, HF prevalence rises due to an aging population and improved survival rates.

Approach:

  • This review synthesizes contemporary data on the global burden of heart failure.
  • It provides updated worldwide estimates for HF prevalence, incidence, outcomes, and costs.
  • The review addresses geographical variations and data gaps, particularly from developing countries.

Key Points:

  • HF prevalence is increasing globally, despite stabilizing incidence in industrialized countries.
  • Factors contributing to rising prevalence include population aging and enhanced cardiovascular disease management.
  • Significant data gaps exist for HF epidemiology in developing nations, where the condition may present differently.

Conclusions:

  • A comprehensive understanding of the global HF burden is crucial for public health strategies.
  • Updated epidemiological data are essential for addressing the growing challenge of heart failure worldwide.
  • Further research is needed to elucidate HF characteristics and management in diverse global settings.

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