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Global burden of heart failure: a comprehensive and updated review of epidemiology
Gianluigi Savarese1,2, Peter Moritz Becher1,3, Lars H Lund1,2
1Division of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Insights
Heart failure (HF) affects over 64 million globally, posing a significant public health challenge. Its increasing prevalence, driven by aging populations and better treatments, necessitates updated global burden estimates.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Heart failure (HF) is a critical global health issue with high morbidity, mortality, and economic impact.
- Over 64 million individuals worldwide are affected by HF, highlighting its substantial burden.
- While incidence declines in developed nations, HF prevalence rises due to an aging population and improved survival rates.
Approach:
- This review synthesizes contemporary data on the global burden of heart failure.
- It provides updated worldwide estimates for HF prevalence, incidence, outcomes, and costs.
- The review addresses geographical variations and data gaps, particularly from developing countries.
Key Points:
- HF prevalence is increasing globally, despite stabilizing incidence in industrialized countries.
- Factors contributing to rising prevalence include population aging and enhanced cardiovascular disease management.
- Significant data gaps exist for HF epidemiology in developing nations, where the condition may present differently.
Conclusions:
- A comprehensive understanding of the global HF burden is crucial for public health strategies.
- Updated epidemiological data are essential for addressing the growing challenge of heart failure worldwide.
- Further research is needed to elucidate HF characteristics and management in diverse global settings.
Abstract:
Heart Failure (HF) is a multi-faceted and life-threatening syndrome characterized by significant morbidity and mortality, poor functional capacity and quality of life, and high costs. HF affects more than 64 million people worldwide. Therefore, attempts to decrease its social and economic burden have become a major global public health priority. While the incidence of HF has stabilized and seems to be declining in industrialized countries, the prevalence is increasing due to the ageing of the population, improved treatment of and survival with ischaemic heart disease, and the availability of effective evidence-based therapies prolonging life in patients with HF. There are geographical variations in HF epidemiology. There is substantial lack of data from developing countries, where HF exhibits different features compared with that observed in the Western world. In this review, we provide a contemporary overview on the global burden of HF, providing updated estimates on prevalence, incidence, outcomes, and costs worldwide.
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