Smartphone-based microfluidic chip modified using pyrrolidine-1-dithiocarboxylic acid for simultaneous colorimetric...

A portable µ-chip-based colorimetric device was developed for the determination of Cr³⁺ and Al³⁺ ions. The silver nanoparticles were modified with pyrrolidine-1-dithiocarboxylic acid ammonium salt as a novel ligand for the first time. The color of modified AgNPs in the test zone immediately changes after the addition of Cr³⁺ and Al³⁺ ions. The resulting color changes were detected by the naked eye or were taken by a smartphone camera. The obtained images were analyzed by RGB software to assay the Cr³⁺ and Al³⁺ ions concentration. Under optimized experimental conditions, the linear ranges are 0.1-220 and 0.01-250 µM for Cr³⁺ and Al³⁺ ions, respectively. The probe has a limit of detections of 10.66 and 3.55 nM for Cr³⁺ and Al³⁺ in an aqueous solution. In the case of µ-chip, the concentration ranges are 0.1-200 μM and 0.01-220 μM for Cr³⁺ and Al³⁺ ions, with detection limits of 9.18 and 2.30 nM, respectively. The µ-chip showed great potential as a fast detection tool for the monitoring of Cr³⁺ and Al³⁺ ions in real samples such as river water samples.