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COVID-19 and the cardiovascular system: an update
Joshua K Salabei1, Zekarias T Asnake1, Zeeshan H Ismail1
1Department of Internal Medicine, University of Central Florida School of Medicine/North Florida Regional Medical Center, Gainesville, USA.
COVID-19 can cause cardiogenic shock through mechanisms like cytokine storm and myocarditis. This review covers cardiovascular risks and treatments, including vasopressors and inotropes, for managing shock in COVID-19 patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathophysiology
Background:
- COVID-19 (Coronavirus Disease 2019) is a global health crisis with significant mortality.
- Extrapulmonary manifestations of COVID-19 are increasingly recognized, particularly cardiovascular complications.
- Cardiogenic shock is a serious complication observed in COVID-19 patients due to viral affinity for cardiovascular cells.
Purpose of the Study:
- To review the link between the cardiovascular system and COVID-19 infection.
- To focus on mechanisms leading to cardiogenic shock in COVID-19.
- To provide a quick reference for managing cardiovascular complications.
Main Methods:
- Literature review focusing on COVID-19 and cardiovascular pathophysiology.
- Discussion of mechanisms including cytokine storm, myocarditis, and myocardial infarction.
- Overview of cardiovascular risk factors and shock management strategies.
Main Results:
- COVID-19 affects the cardiovascular system through various mechanisms.
- Cytokine storm, direct viral myocarditis, and myocardial infarction contribute to cardiogenic shock.
- Cardiovascular risk factors impact disease prognosis in COVID-19 patients.
Conclusions:
- Understanding the cardiovascular impact of COVID-19 is crucial for patient management.
- Effective management of cardiogenic shock requires knowledge of underlying mechanisms and appropriate therapies.
- This review serves as a reference for optimizing care for COVID-19 patients with cardiovascular complications.
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